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1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride

Basic Information

  • CAS No.: 83783-49-7
  • Purity: 99%
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Details

Manufacturer supply top purity 1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride 83783-49-7 with ISO standards

  • Molecular Formula: C10H7 Cl3 O
  • Molecular Weight: 249.524
  • Vapor Pressure: 0.000496mmHg at 25°C 
  • Boiling Point: 313.5°C at 760 mmHg 
  • Flash Point: 131.7°C 
  • PSA: 17.07000 
  • Density: 1.504g/cm3 
  • LogP: 3.79040 

1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride(Cas 83783-49-7) Usage

General Description

1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride is a chemical compound with the molecular formula C10H7Cl2O. It is a derivative of cyclopropane and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride is a reactive and highly toxic substance that can cause severe skin and eye irritation upon contact. It is also a powerful irritant to the respiratory system when inhaled. Therefore, proper safety precautions, such as wearing protective clothing and handling it in a well-ventilated area, should be followed when working with this chemical. Additionally, it should be stored in a cool, dry place away from heat and open flames to prevent the risk of fire or explosion.

InChI:InChI=1/C10H7Cl3O/c11-6-1-2-7(8(12)5-6)10(3-4-10)9(13)14/h1-2,5H,3-4H2

83783-49-7 Relevant articles

Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones

Meza-Avi?a, Maria Elena,Lingerfelt, Mary A.,Console-Bram, Linda M.,Gamage, Thomas F.,Sharir, Haleli,Gettys, Kristen E.,Hurst, Dow P.,Kotsikorou, Evangelia,Shore, Derek M.,Caron, Marc G.,Rao, Narasinga,Barak, Larry S.,Abood, Mary E.,Reggio, Patricia H.,Croatt, Mitchell P.

supporting information, p. 1827 - 1830 (2016/12/22)

A series of 1,3,4-oxadiazol-2-ones was s...

Systematic investigation of halogen bonding in protein-ligand interactions

Hardegger, Leo A.,Kuhn, Bernd,Spinnler, Beat,Anselm, Lilli,Ecabert, Robert,Stihle, Martine,Gsell, Bernard,Thoma, Ralf,Diez, Joachim,Benz, Joerg,Plancher, Jean-Marc,Hartmann, Guido,Banner, David W.,Haap, Wolfgang,Diederich, Francois

supporting information; experimental part, p. 314 - 318 (2011/02/28)

Halogen bonding triggers activity: Incre...

Synthesis of β-, γ-, and δ-lactams via Pd(II)-catalyzed C-H activation reactions

Wasa, Masayuki,Yu, Jin-Quan

supporting information; experimental part, p. 14058 - 14059 (2009/03/11)

Pd(II)-catalyzed intramolecular aminatio...

83783-49-7 Process route

1-(2,4-dichlorophenyl)cyclopropane-1-carboxylic acid

1-(2,4-dichlorophenyl)cyclopropane-1-carboxylic acid

C<sub>10</sub>H<sub>7</sub>Cl<sub>3</sub>O
83783-49-7

C10 H7 Cl3 O

Conditions
Conditions Yield
With oxalyl dichloride;
With thionyl chloride; In dichloromethane; at 22 ℃; for 20h; Inert atmosphere;
With thionyl chloride; In dichloromethane; at 50 ℃; for 1h; Inert atmosphere;
piperidin-4-one
41661-47-6

piperidin-4-one

C<sub>10</sub>H<sub>7</sub>Cl<sub>3</sub>O
83783-49-7

C10 H7 Cl3 O

1-[1-(2,4,-dichlorophenyl)cyclopropanecarbonyl]piperidin-4-one

1-[1-(2,4,-dichlorophenyl)cyclopropanecarbonyl]piperidin-4-one

Conditions
Conditions Yield
With triethylamine; In tetrahydrofuran; dichloromethane; at 0 - 50 ℃; for 24.25h; Inert atmosphere;
540 mg

83783-49-7 Downstream products

  • 1072810-08-2
    1072810-08-2

    C11 H11 Cl2 NO2