1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride
Basic Information
- CAS No.: 83783-49-7
- Purity: 99%
Details
Manufacturer supply top purity 1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride 83783-49-7 with ISO standards
- Molecular Formula: C10H7 Cl3 O
- Molecular Weight: 249.524
- Vapor Pressure: 0.000496mmHg at 25°C
- Boiling Point: 313.5°C at 760 mmHg
- Flash Point: 131.7°C
- PSA: 17.07000
- Density: 1.504g/cm3
- LogP: 3.79040
1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride(Cas 83783-49-7) Usage
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General Description |
1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride is a chemical compound with the molecular formula C10H7Cl2O. It is a derivative of cyclopropane and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 1-(2,4-dichlorophenyl)cyclopropanecarbonyl chloride is a reactive and highly toxic substance that can cause severe skin and eye irritation upon contact. It is also a powerful irritant to the respiratory system when inhaled. Therefore, proper safety precautions, such as wearing protective clothing and handling it in a well-ventilated area, should be followed when working with this chemical. Additionally, it should be stored in a cool, dry place away from heat and open flames to prevent the risk of fire or explosion. |
InChI:InChI=1/C10H7Cl3O/c11-6-1-2-7(8(12)5-6)10(3-4-10)9(13)14/h1-2,5H,3-4H2
83783-49-7 Relevant articles
Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones
Meza-Avi?a, Maria Elena,Lingerfelt, Mary A.,Console-Bram, Linda M.,Gamage, Thomas F.,Sharir, Haleli,Gettys, Kristen E.,Hurst, Dow P.,Kotsikorou, Evangelia,Shore, Derek M.,Caron, Marc G.,Rao, Narasinga,Barak, Larry S.,Abood, Mary E.,Reggio, Patricia H.,Croatt, Mitchell P.
supporting information, p. 1827 - 1830 (2016/12/22)
A series of 1,3,4-oxadiazol-2-ones was s...
Systematic investigation of halogen bonding in protein-ligand interactions
Hardegger, Leo A.,Kuhn, Bernd,Spinnler, Beat,Anselm, Lilli,Ecabert, Robert,Stihle, Martine,Gsell, Bernard,Thoma, Ralf,Diez, Joachim,Benz, Joerg,Plancher, Jean-Marc,Hartmann, Guido,Banner, David W.,Haap, Wolfgang,Diederich, Francois
supporting information; experimental part, p. 314 - 318 (2011/02/28)
Halogen bonding triggers activity: Incre...
Synthesis of β-, γ-, and δ-lactams via Pd(II)-catalyzed C-H activation reactions
Wasa, Masayuki,Yu, Jin-Quan
supporting information; experimental part, p. 14058 - 14059 (2009/03/11)
Pd(II)-catalyzed intramolecular aminatio...
83783-49-7 Process route
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1-(2,4-dichlorophenyl)cyclopropane-1-carboxylic acid
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83783-49-7
C10 H7 Cl3 O
| Conditions | Yield |
|---|---|
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With
oxalyl dichloride;
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|
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With
thionyl chloride;
In
dichloromethane;
at 22 ℃;
for 20h;
Inert atmosphere;
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With
thionyl chloride;
In
dichloromethane;
at 50 ℃;
for 1h;
Inert atmosphere;
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41661-47-6
piperidin-4-one
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83783-49-7
C10 H7 Cl3 O
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1-[1-(2,4,-dichlorophenyl)cyclopropanecarbonyl]piperidin-4-one
| Conditions | Yield |
|---|---|
|
With
triethylamine;
In
tetrahydrofuran; dichloromethane;
at 0 - 50 ℃;
for 24.25h;
Inert atmosphere;
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540 mg
|
83783-49-7 Downstream products
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1072810-08-2
C11 H11 Cl2 NO2
Relative Products
- 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)azo]-N-[4-[[1-[2-[4-(hexadecyloxy)phenyl]-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]ethyl]sulphonyl]phenyl]-4-methoxybenzenesulphonamide
- (butylstannylidyne)tris(thioethane-1,2-diyl) tris[(9Z,12Z)-octadeca-9,12-dienoate]
- 7-hydroxy-8-[[4'-[(4-hydroxyphenyl)azo]-3,3'-dimethyl[1,1'-biphenyl]-4-yl]azo]naphthalene-1,3-disulphonic acid
- 3-Bromofuran
- TETRAPHENYLBIPHOSPHINE
- 2-ethyl-1-(2,4,6-trimethylbenzoyl)-1H-imidazole
- Carbenoxolone
- 2-AMINO-4-IMINO-2-THIAZOLINE HYDROCHLORIDE
- Propyltriphenylphosphonium bromide
- 4-(1,1,3,3-tetramethylbutyl)pyrocatechol
- 4,5-Dihydro-5-(4-fluorophenyl)-2(3H)-furanone
- ALLOCRYPTOPINE
- 2-Bromo-1-tetralone
- [[(diethylamino)thioxomethyl]thio]acetic acid
- 2-Bromophenol
- [[(aminocarbonyl)amino]carbonyl]oxamide
- disodium 1-[2-(carboxymethoxy)ethyl]-1-(carboxymethyl)-4,5-dihydro-2-undecyl-1H-imidazolium chloride
- 2-CYANOETHYLMETHYLDIETHOXYSILANE
- ALUMINUM DI(SEC-BUTOXIDE)ACETOACETIC ESTER CHELATE
- 1-[2-[(2-chlorophenyl)amino]ethyl]-4-methylpyridinium chloride