2-PHENYL-1,3-INDANDIONE

Cost-effective and customizable 2-PHENYL-1,3-INDANDIONE 83-12-5 for sale We provide high quality 2-PHENYL-1,3-INDANDIONE (CAS 83-12-5), at a very affordable prices to our customers.

1.What is the 2-PHENYL-1,3-INDANDIONE ?

Phenindione is an anticoagulant and vitamin K antagonist. It inhibits the reduction of vitamin K1 epoxide to vitamin K1 by vitamin K1 epoxide reductase in rat liver homogenates in a concentration-dependent manner. In vivo, phenindione (500 mg/kg) inhibits prothrombin synthesis and conversion of vitamin K1 epoxide to vitamin K1 in rats by 50 and 57%, respectively. Dietary administration of phenindione (4 mg/kg per day) inhibits aortic atherosclerosis or intracardial thrombosis in rat models of diet-induced atherosclerosis or intravascular thrombosis, respectively.

Like coumarin derivatives, phenindione, a compound of the indandione class, acts by altering biosynthesis of coagulant proteins in the liver. It is used for preventing and treating thrombosis, thrombophlebitis, and thromboembolism. However, because of a number of side effects such as polyurea, polydipsia, tachycardia, and others, it is rarely used in practical medicine.

2.What is the CAS number for 2-PHENYL-1,3-INDANDIONE ?

The CAS number of 2-PHENYL-1,3-INDANDIONE is 83-12-5.

More information of 2-PHENYL-1,3-INDANDIONE 83-12-5 are:

3.What is the molecular formula of 2-PHENYL-1,3-INDANDIONE ?

The chemical formula of?2-PHENYL-1,3-INDANDIONE is C15H10 O2 which containing 15 Carbon atoms,10 Hydrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of 2-PHENYL-1,3-INDANDIONE is 222.243

4.What is 2-PHENYL-1,3-INDANDIONE(83-12-5)used for?

Phenindione is an anticoagulant and vitamin K antagonist. It inhibits the reduction of vitamin K1 epoxide to vitamin K1 by vitamin K1 epoxide reductase in rat liver homogenates in a concentration-dependent manner. In vivo, phenindione (500 mg/kg) inhibits prothrombin synthesis and conversion of vitamin K1 epoxide to vitamin K1 in rats by 50 and 57%, respectively. Dietary administration of phenindione (4 mg/kg per day) inhibits aortic atherosclerosis or intracardial thrombosis in rat models of diet-induced atherosclerosis or intravascular thrombosis, respectively.

InChI:InChI=1/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,16H

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5.Cost-effective and customizable 2-PHENYL-1,3-INDANDIONE 83-12-5 for sale

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