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Dansyl chloride

Basic Information

  • CAS No.: 605-65-2
  • Purity: 99%
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What is the Dansyl chloride ?

Dansyl chloride is yellow to orange-yellow crystalline powder, while it's Molecular Formula is C12H12ClNO2S. Dansyl chloride is a fluorogenic reagent used for protein, N-terminal amino acid and peptide detection by reverse phase high performance liquid chromatography (HPLC). It is also used to determine the degree of labeling in chymotrypsin and ovalbumin. It acts as a precursor for the synthesis of other derivatives like dansyl amide.

What is the CAS number for Dansyl chloride ?

The CAS number of Dansyl chloride is 605-65-2.

More information of Dansyl chloride 605-65-2 are:

Synonyms

1-(Dimethylamino)-5-naphthalenesulfonylchloride;5-(Dimethylamino)-1-naphthalenesulfonyl chloride;5-(N,N-Dimethylamino)-1-naphthalenesulfonylchloride;DNS chloride;NSC 83616;

CAS?Number

605-65-2

Molecular Formula

C12H12ClNO2S

Molecular Weight

269.752

Density

1.361 g/cm3

Melting Point

70-73 °C(lit.)

Boiling Point

371.3 °C at 760 mmHg

Flash Point

178.4 °C

HS CODE

29214980

PSA

45.76000

LogP

3.91410

Pka

2.38±0.40(Predicted)

What is Dansyl chloride (605-65-2) used for?

Dansyl chloride, also known as 5-Dimethylaminonaphthalene-1-sulfonyl chloride (CAS 605-65-2), is a fluorogenic reagent that is widely used in the field of biochemistry and biophysical studies. It is non-fluorescent until it reacts with amines, forming Dansyl amides which exhibit environmentally sensitive fluorescence quantum yields, emission maxima, and large Stokes shifts. This unique property has made Dansyl chloride an important tool for various applications in research and analysis.

InChI:InChI=1/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3

Articles related to Dansyl chloride:

Article

Source

Preparation method of 6-deuterated dansyl chloride

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Paragraph 0076-0077; 0079, (2020/12/14)

A convenient, one-pot procedure for the preparation of acyl and sulfonyl fluorides using Cl3CCN, Ph3P, and TBAF(t -BuOH) 4

Kim, Joong-Gon,Jang, Doo Ok

experimental part, p. 3049 - 3052 (2011/02/25)

How to get the best price on Dansyl chloride?

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